Schizophrenia
Schizophrenia is a serious, chronic mental disorder affecting how a person thinks, feels, and behaves. People with schizophrenia may experience hallucinations, delusions, disorganized thinking, and impaired functioning. With proper treatment, many people with schizophrenia can manage symptoms and lead productive lives.
Symptoms
Causes
- Complex interaction of genetics and environment
- Multiple genes contribute to risk
- Brain chemistry: dopamine and glutamate imbalances
- Brain structure differences (enlarged ventricles, reduced cortical volume)
- Prenatal risk factors (infections, malnutrition, stress)
- Cannabis use during adolescence increases risk in vulnerable individuals
Diagnosis
Requires at least 6 months of symptoms with at least 1 month of active-phase symptoms (delusions, hallucinations, disorganized speech). Must rule out schizoaffective disorder, mood disorders with psychotic features, substance-induced psychosis, and medical conditions. Brain imaging and blood tests help exclude other causes.
Treatment Options
When to Seek Help
Seek immediate help if someone is hearing voices or seeing things others don't, expressing bizarre or paranoid beliefs, showing significant personality changes, withdrawing from social contact, or showing declining ability to care for themselves.